Dirhodium tetraacetatum CAS:15956-28-2 99% Crystallum viridi-nigrum
| Catalogue Number | XD90641 |
| Product Name | Dirhodium tetraacetate |
| CAS | 15956-28-2 |
| Formulae hypotheticae | C8H12O8Rh2 |
| M. Pondus | 441.987 |
| Repono Details | Ambiens |
| Tariff Code harmonized | 28439000 |
Product Specification
| Aspectus | Viridis-nigris crystallis |
| Assay | 99% |
N7/O6 interationes aequatoriales ligaturae antitumoris complexi activi Rh(2)(OAc)(4)(H(2)O)(2)(OAc(-) = CH(3)CO(2)(-)) cum fragmento DNA d(GpG) sine spectroscopio NMR determinatum est.Priores X-radii determinationes crystallographicae capitis-ad-capitis (HH) et capitis ad caudam (HT) adducta dirhodi tetraacetate cum 9-ethylguanine (9-EtGH) revelata inusitata traiectione N7/O6 nucleobasum guaninarum quae Rh. -Rh iuncta.Absentia protonationis N7 ad humilem pH et auctum notabile in acorem N1-H (pK(a) circiter 5.7 comparatum ad 8.5 pro N7 tantum adductas platinum ligatum), ex pH dependentiae titrationes purini H8 propositae. )H NMR resonantiae pro Rh(2)(OAc)(2)(9-EtG)(2) et Rh(2)(OAc)(2-)[d(GpG)] consentaneae sunt cum ligatione bidentato N7/O6 guani nucleobases.Valores pK(a) aestimantur pro protonatione N1-H, a dependentiae pH studiis C6 et C2 (13)C NMR resonantiae pro Rh(2)(OAc)(2)(9-EtG)( 2) isomers, concurrunt cum t caligarum ex H8 (1)H NMR titrationes resonantiae.Comparatio horum (13)C NMR sonorum C6 et C2 ad dirhodio adductorum Rh(2)(OAc)(2)(9-EtG)(2) et Rh(2)(OAc)(2)[d(GpG )] sonoribus ligandi solutorum respondentibus [ad pH 7.0 pro 9-EtGH et pH 8.0 pro d(GpG)], ostendit substantiales vices Deltadeltae circa 11.0 et 6.0 ppm pro C6 et C2 respective;hae vices reflectunt effectum ligationis O6 ad centra dirhodium et amplificationem sequentem in acorem N1-H.Vehemens H8/H8 ROE culmina transversalis in 2D ROESY NMR spectrum Rh(2)(OAc)(2)[d(GpG)] indicant dispositionem capitis ad caput basium guaninarum.RH(2)(OAc)(2)[d(GpG)] adductas exhibet duos conformatores majores dextratos, HH1 R et HH2 R, cum HH1 R triplo copiosiorem quam insolitam utriusque R. HH2 R. adducta repercussio sacchari anulorum 5'-G ad C3'-endo (N-type), retentio C2'-endo (S-type) conformationis ad gs gs sacchari 3'-G, et respectu anti orientationis. ad glycosyl vincula.Lineamenta structurae pro Rh(2)(OAc)(2))[d(GpG)] per NMR spectroscopia comparata sunt his simillima pro cis-[Pt(NH(3))(2))[d( GpG)]] et exemplaria hypothetica corroborant.
