Adenosine 5′-monophosphate disodium salis Cas:4578-31-8
| Catalogue Number | XD90587 |
| Product Name | Adenosine 5'-monophosphate disodium salis |
| CAS | 4578-31-8 |
| Formulae hypotheticae | C10H12N5Na2O7P |
| M. Pondus | 391.18 |
| Repono Details | Ambiens |
| Tariff Code harmonized | 29349990 |
Product Specification
| Aspectus | Album vel off pulveris albi |
| Assay | 99% |
| Metalla gravis | <10ppm |
| Repono Temperature | +20 ° C |
| Aqua Content | <26.0% |
Cras pharmacodynamica praeter pharmacokinetica una est strategies ad individuandum mycophenolatum mofetilis therapiae.Propositum huius studii erat ut liquidum chromatographiae sensitivum, tandem spectrometriae massae (LC-MS/MS) evolveret, aestimandis methodis pharmacokineticorum et pharmacodynamica acidi mycophenolici (MPA).Concentrationes acidi mycophenolici glucuronidis (MPAG), acidi mycophenolici acyl-glucuronidis, nec non MPA et MPAG soluti, determinatae sunt, et inosine-5'-monophosphate dehydrogenasis activitatis xanthosine-5'-monophosphatae productorum metiendis (XMP. ) et adenosinum intracellulare 5'-monophosphatum post incubationem sanguinis peripherici mononuclearis (PBMC) lysatis.Liberi metalli Mastro(TM) columnae et duo exemplaria gradientia adhibita sunt ad quantitatem limitis XMP ad 0.1 μM emendandam.In ambitus intentionis clinicae MPA, linearitas curvae calibrationis, inter- et intra dies praecisionem et diligentiam relev ant US Cibus et medicamentis administrationis viasque satisfecit.MPA concentrationes in caule hematopoietico cellae transplantandi (HSCT) aegros ab enzyme primordium determinatos et methodum praesentem LC-MS/MS bonam correlationem (r(2) = 0.95, p < 0.001) ostendit.In hoc studio modos sensitivos et validos LC-MS/MS referimus ad aestimandas pharmacokineticas et pharmacodynamicas MPA, quae satis sentiuntur ad aestimandas quantitates parvas lysatorum PBMC collectorum paulo post HSCT.
