Streptomycin sulphate CAS:3810-74-0 Pulvis albus
| Catalogue Number | XD90361 |
| Product Name | Streptomycin sulfate |
| CAS | 3810-74-0 |
| Formulae hypotheticae | (C21H39N7O12)2·3H2SO4 |
| M. Pondus | 1457.39 |
| Repono Details | 2 ad 8 °C |
| Tariff Code harmonized | 29412080 |
Product Specification
| Gradus | USP36/EP8.0 |
| pH | 4.5-7.0 |
| Damnum in Siccatio | ≤7.0% |
| Assay | ≥720IU/MG |
| Sulfate | 18.0~ 21.5% |
| Aspectus | Pulvis albus vel fere albus, in aqua perquam solutus, in ethanolo fere solubilis. |
| Methanol | ≥0.3% |
| Streptomycin B | ≤3.0% |
| Colorimetric Test | ≥900% |
| Acidum SULPHURATUS | ≤1.0% |
| Attenti sodium sulphite content | ≤0.4% |
Quamvis etiologia discorum intervertebralium degenerationis male intellecta sit, tamen aditus est ad impediendam hanc processum apoptosin inhibendam.In studio currenti, effectus anti‑apoptotici carboxymethylatae chitosani (CMCS) in nucleo pulposi (NP) cellulae exploratae sunt eo consilio ut augendae discus cellae superesset.Rat NP cellulae in vitro solitae et excultae sunt, et hydrogenii peroxide (H2O2) exemplar cellae NP ad aedificandum adhibita sunt.Cellula viability aestimata est cum cella computandi ornamentum 8 primordium.Proportio cellularum apoptoticorum ab annexin V‑fluorescein isothiocyanate (FITC) et propidium iodidum duplex analysin inficiens, et morphologiam ab Hoechst 33342 inficiens observavit.Membrana mitochondrialis potentialis NP cellularum aestimata est a rhodamine 123 fluorescentia tincta.Inversa transcriptio (RT) ‑ catenis quantitatis polymerasis reactionis (qPCR) fiebat ad metiri mRNA gradus oxydi nitrici inducibilis synthaseos (iNOS), caspase‑3, lymphoma B‑cell (Bcl)‑2, typus II collagen et aggrecan.Analysis occidentalis macula facta est ad deprehendendas gradus interdum in iNOS et Bcl‑2.In annexin V‑FITC/PI et Hoechst 33342 proventuum maculas significavit CMCS posse prohibere NP cellulas ab apoptosin modo dose-dependente.Rhodamine 123 maculavit declaravit CMCS imminutionem membranae mitochondrialis potentialem in H2O2‑ tractatam NP cellulis redegisse.Caspase‑3 reduci et activitatem Bcl‑2 augeri deprehensi sunt in cellulis CMCS‑tractatis ab RT‑qPCR et analysi occidentali.CMCS propagationem et secretionem typorum II collageni et aggrecan in H2O2 tractatam NP cellulis promovebat.CMCS significatum est efficax esse ad mortem cellam apoptoticam prohibendam in vitro, demonstrans commoda potentiales huius therapeuticae accessus in disco degeneratione moderante.
