Spiramycin Cas: 8025-81-8
| Catalogue Number | XD90452 |
| Product Name | Spiramycin |
| CAS | 8025-81-8 |
| Formulae hypotheticae | C43H74N2O14 |
| M. Pondus | 843.05 |
| Repono Details | 2 ad 8 °C |
| Tariff Code harmonized | 29419000 |
Product Specification
| Aspectus | Alba pulveris |
| Assay | >4100IU/mg |
| Metalla gravis | < 20ppm |
| Damnum in Siccatio | < 3.5% |
| Cinis sulphated | < 1.0% |
| Ethanol | < 2.0% |
| Imprimis gyrationis optica | -85 ad -80 deg |
Streptomyces ambofaciens componit macrolides spiramycinum antibioticum.Botrus gene biosyntheticus pro spiramycin insignitus est pro S. ambofaciens.Praeter gene regulatorium srmR (srm22), antea notatum (M. Geistlich et al., Mol. Microbiol. 6:2019-2029, 1992), tria genera regulatoria putativa per analysim sequentiam notata sunt.Analysis gene expressionis et inactivationis gene experimenta demonstraverunt solum unum ex his tribus genes, srm40, maiorem partem habere in ordinatione spiramycin biosynthesis.Disruptio srm22 vel srm40 productio spiramycinum eliminata est, dum aucta productione spiramycinum overexpressio eorum.Analysis expressio fiebat ex transumpto-PCR (RT-PCR) omnium generum botri in cola silvestrium et in srm22 (srmR) et srm40 mutantes deletionis.Eventus analysis expressionis, una cum experimentis complementationis, significavit Srm22 requiri ad expressionem srm40, Srm40 esse viam activatorem specialem qui maxime, etsi non omnes, genesis biosynthetici moderantis.
