BCIP-Toluidine)5-bromo-4-chloro-3-indolylphosphate-p-toluidine salis Cas: 6578-06-9 99% Albae ad levem pulverem brunneum
| Catalogue Number | XD90137 |
| Product Name | BCIP-Toluidine)5-bromo-4-chloro-3-indolylphosphate-p-toluidine salis |
| CAS | 6578-06-9 |
| Formulae hypotheticae | C8H5BrClNO4P·C7H10N |
| M. Pondus | 433.62 |
| Repono Details | -15 ad -20 °C |
| Tariff Code harmonized | 29339980 |
Product Specification
| Aspectus | Album / lux brunneis pulveris |
| Assay | ≥ 99% |
| Liquescens punctum | 194-195 C |
| Ferveret | 580.2°C at 760 mmHg |
| Mico punctum | 304.7°C |
| Solubilitas | DMF: 20 mg/mL |
| Solubilitas | solutum in dimethylformamide, in aqua solutum. |
| Sensibilitas | Lumen sensitivum, sensitivum aeri, sensitivum calori |
Actio biologica: BCIP (BCIP p-toluidine salis; X-phosphate p-toluidine salis) est subiecta chromogenica ob detectionem actionis phosphatae alcalini colorimetricae.
Shiga toxins (Stxs) producuntur ab Escherichia coli (EHEC) enterohemorrhagic, quae causant contagiones humanos cum eventu fatali saepe.Vero cellulae lineae, ex renibus simiae viridis Africanae derivatae, vexillum aureum significant ad effectus cytotoxicos Stxs determinandos.Quamvis in global usum, scientia de accuratis structurae glycosphingolipidorum Stx receptoris (GSLs) et conventus eorum in ratibus lipidis pauper est.Hic exhibemus analysin comprehensivam structuralem Stx receptoris GSLs earumque distributionem ad membranas renitentes (DRMs), quae paratae sunt e cellulis Vero-B4 et ut ratis adaequatione lipidorum adhibita.In globotriaosylceramide (Gb3Cer) et globotetraosylceramide (Gb4Cer) notavimus ut receptores GSL pro Stx1a, Stx2a, et Stx2e subtypis utentes TLC detegendo detectionem cum MS coniunctam.Receptor Stx rarus, globopentaosylceramide (Gb5Cer, Galβ3GalNAcβ3Galα4Galβ4Glcβ1Cer), quae specie agnita est (praeter Gb3Cer et Gb4Cer) a Stx2e, plene structurae insignita est.Lipoformes Stx receptoris GSLs inventae sunt ut medietates ceramidae maxime sphingosinae compositae (d18:1) et C24:0/C24:1 vel C16:0 acidum pingue.Praeterea, occursus cum ratis lipidorum figmentis, SM et cholesterol, in DRMs consociatio GSL cum microdomains membranaceis suggessit.Hoc studium fundamentum praebet ulteriori explorandi impulsum ratis lipidis-consociati Stx receptorum ad nocumentum toxin mediatum Vero-B4 cellularum.
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