5-Methylphenazinium methosulfatum Cas: 299-11-6 99% Nigrae virides vel brunneae
| Catalogue Number | XD90224 |
| Product Name | 5-Methylphenazinium methosulfate |
| CAS | 299-11-6 |
| Formulae hypotheticae | C14H14N2O4S |
| M. Pondus | 306.337 |
| Repono Details | -15 ad -20 °C |
| Tariff Code harmonized | 29339980 |
Product Specification
| Liquescens punctum | 158-160 °C. |
| Assay | 99% |
| Forma | Firmus |
| Aspectus | Tenebris viridi ad brunneis pulveris |
N-3 acida pinguia polyunsaturata acida eicosapentaenoica (EPA) et acidi docosahexaenoici (DHA) ostensa sunt augere effectum medicamentorum chemotherapeuticorum in studiis clinicis in aegros cancer et ad mortem in vitro cellam tumorem apoptoticum inducere.Usque nunc, EPA et DHA in myeloma multiplicibus numquam explorata sunt (MM).Humanae myeloma cellulae (L363, OPM-1, OPM-2 et U266) et normales cellae peripherales sanguinis mononucleares EPA et DHA expositae erant, et effectus in functione mitochondriali et apoptosin, caspase-3 activatione, elocutione gene et toxicitate medicamento metiebantur.Patefacio ad EPA et DHA apoptosin inducebat et sensus augebatur ad bortezomib in cellulis MM.Maxime viability humanorum peripheralium mononucleares cellulas normales non afficiebant.Nuntius RNA expressio vestitus ostendit EPA et DHA genes involutos multiplicibus meatus significationibus implicari, quas factor nuclearis (NF) κB, Notch, Hedgehog, oxidativa et Wnt.EPA et DHA actio inhibuit NFκB et apo ptosis inducitur per perturbationem mitochondrialem et activationem caspasim-3.Studium nostrum suggerit EPA et DHA effectus selectivos cytotoxicos in MM inducere et sensum augere ad bortezomib et ulteriorem explorationem in potentiali applicatione horum n-3 acida pinguia polyunsaturata in therapia MM inducant.
