2-(3,5-dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-unum Cas:1044871-04-6
Catalogue Number | XD90961 |
Product Name | 2-(3,5-dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one |
CAS | 1044871-04-6 |
Formulae hypotheticae | C24H29N3O4 |
M. Pondus | 423.5 |
Repono Details | |
Tariff Code harmonized |
Product Specification
Aspectus | |
Assay | |
Bunguentum illud | 612.6±65.0 °C (Predicta) |
Density | 1.25±0.1 g/cm3(Predicta) |
Acidum coefficiens | (pKa) 9.54±0.20(Predicta) |
RVX-297 valde potens est, viva voce activa BET inhibitor selectiva pro BD2.IC50s RVX-297 pro BRD2(BD2), BRD3(BD2), BRD4(BD2) erant 0.08, 0.05, et 0.02 µM, respective.RVX-297 vetat expressionem variarum generum inflammatoriae cellae immunis.Efficacia RVX-297 in exemplaribus preclinicis acutae inflammationis et autoimmunitatis.
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